85-6631-83　BLNK Monoclonal Antibody 50ul　BT-MCA0219

特徴

• 背景：This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.

仕様

• サイズ：50ul
• 抗原：Purified recombinant fragment of human BLNK expressed in E. Coli.
• 免疫動物：Mouse
• 交差性：Human,Mouse
• 適用：WB, IHC-p, IF, ICC, FCM, ELISA
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa;
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