85-6631-50 Bcl-10 Monoclonal Antibody 50ul BT-MCA0204
特徴
- 背景:This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
仕様
- サイズ:50ul
- 抗原:Purified recombinant fragment of human Bcl-10 expressed in E. Coli.
- 免疫動物:Mouse
- 交差性:Human,Mouse
- 適用:WB, IHC-p, IF, ICC, FCM, ELISA
- クラス:IgG
- クロナリティ:Monoclonal
- 濃度:1 mg/ml
- 別名:BCL10; CIPER; CLAP; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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85-6631-51
Bcl-10 Monoclonal Antibody 100ul
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85-6631-50
Bcl-10 Monoclonal Antibody 50ul
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