85-6630-91 APP Monoclonal Antibody 50ul BT-MCA0177
特徴
- 背景：This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
仕様
- サイズ：50ul
- 抗原：Purified recombinant fragment of APP expressed in E. Coli.
- 免疫動物：Mouse
- 交差性：Human
- 適用：WB, IHC-p, IF, ELISA
- クラス：IgG
- クロナリティ：Monoclonal
- 濃度：1 mg/ml
- 別名：APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II
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- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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85-6630-91
APP Monoclonal Antibody 50ul
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85-6630-92
APP Monoclonal Antibody 100ul
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