85-6630-79　ApoB Monoclonal Antibody 50ul　BT-MCA0171

特徴

• 背景：This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.

仕様

• サイズ：50ul
• 抗原：Purified recombinant fragment of human ApoB expressed in E. Coli.
• 免疫動物：Mouse
• 交差性：Human
• 適用：WB, IF, ICC, FCM, ELISA
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：APOB; Apolipoprotein B-100; Apo B-100
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