85-6628-59　IDE Monoclonal Antibody（3H4） 20ul　BT-MCA0055

特徴

• 背景：This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been describe

仕様

• サイズ：20ul
• 抗原：Synthetic Peptide of IDE
• 免疫動物：Mouse
• 交差性：Human
• 適用：WB, IHC-p, IF, ICC
• クラス：IgG
• クロナリティ：Monoclonal
• 濃度：1 mg/ml
• 別名：IDE; Insulin-degrading enzyme; Abeta-degrading protease; Insulin protease; Insulinase; Insulysin
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