85-6602-52　TIRAP（Phospho Tyr86） Polyclonal Antibody 20ul　BT-AP14989

特徴

• 背景：The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human TIRAP around the phosphorylation site of Tyr86. AA range:52-101
• 免疫動物：Rabbit
• 交差性：Human, Mouse
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Toll/interleukin-1 receptor domain-containing adapter protein; TIRAP; MAL; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein
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