85-6598-06 CDA7L Polyclonal Antibody 100ul BT-AP14841
特徴
- 背景：Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.,induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line.,miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines. CDCA7L overexpression induces colony formation.,subcellular location:Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.,subunit:Interacts with MYC and PSIP1.,tissue specificity:Ubiquitous. Overexpressed in medulloblastoma.,
仕様
- サイズ：100ul
- 抗原：Synthesized peptide derived from human protein . at AA range: 140-220
- 免疫動物：Rabbit
- 交差性：Human, Rat, Mouse
- 適用：WB, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：Cell division cycle-associated 7-like protein ;Protein JPO2;Transcription factor RAM2
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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85-6598-06
CDA7L Polyclonal Antibody 100ul
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85-6598-05
CDA7L Polyclonal Antibody 50ul
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85-6598-04
CDA7L Polyclonal Antibody 20ul
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掲載カタログ情報
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