85-6594-20　TAB3 Polyclonal Antibody 50ul　BT-AP14707

特徴

• 背景：The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from part region of human protein
• 免疫動物：Rabbit
• 交差性：Human, Mouse
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 ;Mitogen-activated protein kinase kinase kinase 7-interacting protein 3;NF-kappa-B-activating protein 1;TAK1-binding protein 3;TAB-3;TG
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