85-6590-21 Stat6(Phospho Thr645) Polyclonal Antibody 100ul BT-AP14556
特徴
- 背景:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
仕様
- サイズ:100ul
- 抗原:The antiserum was produced against synthesized peptide derived from human STAT6 around the phosphorylation site of Thr645. AA range:612-661
- 免疫動物:Rabbit
- 交差性:Human, Mouse, Rat
- 適用:WB, IHC-p, IF, IP, ELISA
- クラス:IgG
- クロナリティ:Polyclonal
- 濃度:1 mg/ml
- 別名:Signal transducer and activator of transcription 6; STAT6; Signal transducer and activator of transcription 6; IL-4 Stat
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6590-19
Stat6(Phospho Thr645) Polyclonal Antibody 20ul
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85-6590-20
Stat6(Phospho Thr645) Polyclonal Antibody 50ul
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85-6590-21
Stat6(Phospho Thr645) Polyclonal Antibody 100ul
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