85-6589-80　Stat4 Polyclonal Antibody 50ul　BT-AP14541

特徴

• 背景：The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from human Stat4 around the non-phosphorylation site of Y693.
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IHC-p, IF
• クラス：IgG
• クロナリティ：Polyclonal
• 別名：Signal transducer and activator of transcription 4; STAT4; Signal transducer and activator of transcription 4
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