85-6587-29　Bestrophin-1 Polyclonal Antibody 50ul　BT-AP14451

特徴

• 背景：This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

仕様

• サイズ：50ul
• 抗原：Synthetic Peptide of Bestrophin-1
• 免疫動物：Rabbit
• 交差性：Human, Rat, Mouse
• 適用：WB, IHC-p, IF
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Bestrophin-1 ;TU15B;Vitelliform macular dystrophy protein 2; Bestrophin-1; TU15B; Vitelliform macular dystrophy protein 2
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