85-6581-10 SIGIR Polyclonal Antibody 20ul BT-AP14223
特徴
- 背景：Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.,Belongs to the interleukin-1 receptor family.,Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,Contains 1 TIR domain.,subunit:Interacts with IL1R1, IRAK1, TLR4, TLR5, TLR9 and TRAF6. Upon IL-1 stimulation found in a complex at least composed of IL1R1, SIGIRR, MYD88, IRAK1 and TRAF6. Upon stimulation with LPC found in a complex at least composed of TLR4, SIG1IR, MYD88, IRAK1 and TRAF6.,tissue specificity:Mainly expressed in epithelial tissues such as kidney, lung and gut.,
仕様
- サイズ：20ul
- 抗原：Synthesized peptide derived from part region of human protein
- 免疫動物：Rabbit
- 交差性：Human, Rat, Mouse
- 適用：WB, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：Single Ig IL-1-related receptor ;Single Ig IL-1R-related molecule;Single immunoglobulin domain-containing IL1R-related protein;Toll/interleukin-1 receptor 8;TIR8
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6581-10
SIGIR Polyclonal Antibody 20ul
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85-6581-11
SIGIR Polyclonal Antibody 50ul
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85-6581-12
SIGIR Polyclonal Antibody 100ul
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