85-6580-79　AMPK beta 2 Polyclonal Antibody 20ul　BT-AP14212

特徴

• 背景：The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.

仕様

• サイズ：20ul
• 抗原：Recombinant Protein of AMPKβ2
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB
• クラス：IgG
• クロナリティ：Polyclonal
• 別名：5'-AMP-activated protein kinase subunit beta-2; PRKAB2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2
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