85-6572-23　RPGF6 Polyclonal Antibody 50ul　BT-AP13916

特徴

• 背景：Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Contains 1 cyclic nucleotide-binding domain.,Contains 1 N-terminal Ras-GEF domain.,Contains 1 PDZ (DHR) domain.,Contains 1 Ras-associating domain.,Contains 1 Ras-GEF domain.,subcellular location:Upon binding to M-Ras, it translocates to the plasma membrane.,subunit:Interacts with the second PDZ domain of human PTP1e.,tissue specificity:Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas.,

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from human protein . at AA range: 460-540
• 免疫動物：Rabbit
• 交差性：Human, Rat, Mouse
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Rap guanine nucleotide exchange factor 6 ;PDZ domain-containing guanine nucleotide exchange factor 2;PDZ-GEF2;RA-GEF-2
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