85-6561-39　RAMP1 Polyclonal Antibody 100ul　BT-AP13557

特徴

• 背景：The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms.

仕様

• サイズ：100ul
• 抗原：Synthesized peptide derived from part region of human protein
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Receptor activity-modifying protein 1 ;Calcitonin-receptor-like receptor activity-modifying protein 1;CRLR activity-modifying protein 1
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