85-6547-03　PKA alpha cat（Phospho Ser338） Polyclonal Antibody 100ul　BT-AP13081

特徴

• 背景：This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern

仕様

• サイズ：100ul
• 抗原：Synthesized phospho-peptide around the phosphorylation site of human PKAα cat (phospho Ser338)
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：cAMP-dependent protein kinase catalytic subunit alpha; PRKACA; PKACA; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha
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