85-6546-28　Pin1（Phospho Ser16） Polyclonal Antibody 20ul　BT-AP13054

特徴

• 背景：Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human Pin1 around the phosphorylation site of Ser16. AA range:1-50
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat, Monkey
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; PIN1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1
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