85-6543-22　TAK1（Phospho-Ser412） Rabbit Polyclonal Antibody 20ul　BT-AP12948

特徴

• 背景：The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP)| and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1| this protein forms a kinase complex including TRAF6| MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK| MAP2K4/MKK4| and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

仕様

• サイズ：20ul
• 抗原：Synthesized phosho peptide around human TAK1 (Ser412)
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：TAK1 ;Ser412; Mitogen-activated protein kinase kinase kinase 7; EC 2.7.11.25; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1
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