85-6535-34　Smad7 （Acetyl Lys70） Rabbit Polyclonal Antibody 20ul　BT-AP12686

特徴

• 背景：The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding| this complex translocates to the cytoplasm| where it interacts with TGF-beta receptor type-1 (TGFBR1)| leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

仕様

• サイズ：20ul
• 抗原：Synthesized peptide derived from human Smad7 (Acetyl Lys70)
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Smad7 ;Acetyl Lys70; Mothers against decapentaplegic homolog 7; MAD homolog 7; Mothers against DPP homolog 7; Mothers against decapentaplegic homolog 8; MAD homolog 8; Mothers against DPP homolog 8; SMAD family member 7; SMAD 7; Smad7; hSMAD7
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