85-6535-16　Smad1（Phospho Ser214） Rabbit Polyclonal Antibody 20ul　BT-AP12680

特徴

• 背景：Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).|PTM:Phosphorylated on serine by BMP type 1 receptor kinase.|PTM:Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1.|Belongs to the dwarfin/SMAD family.|Contains 1 MH1 (MAD homology 1) domain.|Contains 1 MH2 (MAD homology 2) domain.|subcellular location:Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.|subunit:Interacts with HGS| NANOG and ZCCHC12 (By similarity). May form trimers with another SMAD1 and the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit| CREB-binding protein (CBP)| p300| SMURF1| SMURF2 and HOXC8. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with LBXCOR1.|tissue specificity:Ubiquitous. Highest expression seen in the heart and skeletal muscle.|

仕様

• サイズ：20ul
• 抗原：Synthesized peptide derived from human Smad1 (Phospho Ser214)
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Smad1 ;Phospho Ser214; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1; BSP-1
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