85-6533-65　p300 （Acetyl Lys1542） Polyclonal Antibody 50ul　BT-AP12630

特徴

• 背景：This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

仕様

• サイズ：50ul
• 抗原：Synthesized acetyl-peptide derived from human p300 around the acetylation site of K1542.
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Histone acetyltransferase p300; EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
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