85-6520-33　Presenilin 2 Rabbit Polyclonal Antibody 100ul　BT-AP12190

特徴

• 背景：Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase| an enzyme that cleaves APP. Also| it is thought that the presenilins are involved in the cleavage of the Notch receptor such that| they either directly regulate gamma-secretase activity| or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified.

仕様

• サイズ：100ul
• 抗原：Synthesized peptide derived from human Presenilin 2
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Presenilin 2; Presenilin-2; PS-2; EC 3.4.23.-; AD3LP; AD5; E5-1; STM-2; Presenilin-2 NTF subunit; Presenilin-2 CTF subunit;
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]