85-6513-28　PKA C（Phospho-Thr197） Rabbit Polyclonal Antibody 20ul　BT-AP11958

特徴

• 背景：This gene encodes one of the catalytic subunits of protein kinase A| which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits| in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes| including differentiation| proliferation| and apoptosis. Constitutive activation of this gene caused either by somatic mutations| or genomic duplications of regions that include this gene| have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Altern

仕様

• サイズ：20ul
• 抗原：Synthesized phosho peptide around human PKA C (Thr197)
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：PKA C ;Thr197 ; cAMP-dependent protein kinase catalytic subunit alpha; PKA C-alpha; EC 2.7.11.11
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