85-6510-89　NIPBL Polyclonal Antibody 50ul　BT-AP11879

特徴

• 背景：This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene.

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from human protein . at AA range: 560-640
• 免疫動物：Rabbit
• 交差性：Human, Mouse
• 適用：IHC-p, IF
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Nipped-B-like protein ;Delangin;SCC2 homolog
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