85-6480-55　LDLR Polyclonal Antibody 50ul　BT-AP10875

特徴

• 背景：The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from human protein . at AA range: 540-620
• 免疫動物：Rabbit
• 交差性：Human, Rat, Mouse
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Low-density lipoprotein receptor ;LDL receptor
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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