85-6480-16　Lck（Phospho Tyr393） Polyclonal Antibody 50ul　BT-AP10862

特徴

• 背景：This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human Lck around the phosphorylation site of Tyr393. AA range:361-410
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, IF, ICC, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Tyrosine-protein kinase Lck; LCK; Tyrosine-protein kinase Lck; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; Protein YT16; Proto-oncogene Lck; T cell-specific protein-tyrosine kinase; p56-LCK
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