85-6475-17　KIR3.1（Phospho Ser185） Polyclonal Antibody 100ul　BT-AP10697

特徴

• 背景：Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, at

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from human GIRK1/KIR3.1/KCNJ3 around the phosphorylation site of Ser185. AA range:151-200
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat, Monkey
• 適用：WB, IHC-p, IF, ICC, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：G protein-activated inward rectifier potassium channel 1; KCNJ3; GIRK1; G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K;+ channel Kir3.1; Potassium channel; inwardly rectifying subfamily J member 3
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