85-6456-10　HLA-DM beta Polyclonal Antibody 50ul　BT-AP10063

特徴

• 背景：HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

仕様

• サイズ：50ul
• 抗原：Synthetic peptide from human protein at AA range: 40-100
• 免疫動物：Rabbit
• 交差性：Human, Rat, Mouse
• 適用：IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：HLA class II histocompatibility antigen, DM beta chain ;MHC class II antigen DMB;Really interesting new gene 7 protein; HLA class II histocompatibility antigen, DM beta chain; MHC class II antigen DMB; Really interesting new gene 7 protein
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