85-6438-71 Vav1 Polyclonal Antibody 50ul BT-AP09488
特徴
- 背景：VAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto-oncogene vav is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
- サイズ：50ul
- 抗原：The antiserum was produced against synthesized peptide derived from human VAV1. AA range:141-190
- 免疫動物：Rabbit
- 交差性：Human;Mouse;Rat
- 適用：WB, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：VAV1; VAV; Proto-oncogene vav
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
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- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6438-72
Vav1 Polyclonal Antibody 100ul
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85-6438-70
Vav1 Polyclonal Antibody 20ul
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85-6438-71
Vav1 Polyclonal Antibody 50ul
|
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