85-6424-13 THP Polyclonal Antibody 50ul BT-AP09001
特徴
- 背景:The protein encoded by UMOD (uromodulin) is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in UMOD are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of UMOD results in multiple transcript variants.
仕様
- サイズ:50ul
- 抗原:The antiserum was produced against synthesized peptide derived from human THP. AA range:329-378
- 免疫動物:Rabbit
- 交差性:Human
- 適用:WB, ELISA
- クラス:IgG
- クロナリティ:Polyclonal
- 濃度:1 mg/ml
- 別名:UMOD; Uromodulin; Tamm-Horsfall urinary glycoprotein; THP
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6424-14
THP Polyclonal Antibody 100ul
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85-6424-12
THP Polyclonal Antibody 20ul
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85-6424-13
THP Polyclonal Antibody 50ul
|
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