85-6423-52　TGFBeta3 Polyclonal Antibody 50ul　BT-AP08981

特徴

• 背景：TGFB3 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Transforming growth factor beta-3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human TGF beta3. AA range:261-310
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat;Monkey
• 適用：WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：TGFB3; Transforming growth factor beta-3; TGF-beta-3
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