85-6421-45　TDG Polyclonal Antibody 20ul　BT-AP08909

特徴

• 背景：The protein encoded by TDG (thymine DNA glycosylase) belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. TDG may have a pseudogene in the p arm of chromosome 12.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human TDG. AA range:31-80
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：TDG; G/T mismatch-specific thymine DNA glycosylase; Thymine-DNA glycosylase
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