85-6413-71　Stat6 Polyclonal Antibody 100ul　BT-AP08645

特徴

• 背景：Signal transducer and activator of transcription 6 encoded by STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from human STAT6. AA range:612-661
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat
• 適用：WB, IHC-p, IP, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：STAT6; Signal transducer and activator of transcription 6; IL-4 Stat
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