85-6410-41　SR-2C Polyclonal Antibody 100ul　BT-AP08536

特徴

• 背景：HTR2C encodes a seven-transmembrane G-protein-coupled receptor. The 5-hydroxytryptamine receptor 2C responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from human HTR2C. AA range:395-444
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：HTR2C; HTR1C; 5-hydroxytryptamine receptor 2C; 5-HT-2C; 5-HT2C; 5-HTR2C; 5-hydroxytryptamine receptor 1C; 5-HT-1C; 5-HT1C; Serotonin receptor 2C
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