85-6409-91　8ODP Polyclonal Antibody 50ul　BT-AP08520

特徴

• 背景：Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates| such as 8-oxo-dGTP| 8-oxo-dATP| 2-hydroxy-dATP| and 2-hydroxy rATP| to monophosphates| thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm| with some in the mitochondria| suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants| some of which encode distinct isoforms| have been identified. Additional variants have been observed| but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional| longer is

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from human protein . at AA range: 1-80
• 免疫動物：Rabbit
• 交差性：Human, Rat, Mouse
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：7; 8-dihydro-8-oxoguanine triphosphatase ;EC 3.6.1.55;2-hydroxy-dATP diphosphatase;EC 3.6.1.56;8-oxo-dGTPase;Nucleoside diphosphate-linked moiety X motif 1;Nudix motif 1
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