85-6402-28　Collagen XVIII alpha 1（Cleaved-His1572） Rabbit Polyclonal Antibody 50ul　BT-AP08259

特徴

• 背景：This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins| extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin| a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities| so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants.

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from human Collagen XVIII α1 (Cleaved-His1572)
• 免疫動物：Rabbit
• 交差性：Human, Mouse
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Collagen XVIII α1 ;Cleaved-His1572; Collagen alpha-1;XVIII chain [Cleaved into: Endostatin;
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