85-6400-55　SEMA4A Polyclonal Antibody 50ul　BT-AP08202

特徴

• 背景：SEMA4A encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human SEMA4A. AA range:501-550
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat;Monkey
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：SEMA4A; SEMAB; SEMB; Semaphorin-4A; Semaphorin-B; Sema B
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