85-6398-32 Saposin Polyclonal Antibody 100ul BT-AP08128
特徴
- 背景:PSAP (prosaposin) encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in PSAP have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
仕様
- サイズ:100ul
- 抗原:The antiserum was produced against synthesized peptide derived from human PSAP. AA range:307-356
- 免疫動物:Rabbit
- 交差性:Human
- 適用:WB, IHC-p, ELISA
- クラス:IgG
- クロナリティ:Polyclonal
- 濃度:1 mg/ml
- 別名:PSAP; GLBA; SAP1; Proactivator polypeptide
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6398-30
Saposin Polyclonal Antibody 20ul
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85-6398-32
Saposin Polyclonal Antibody 100ul
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85-6398-31
Saposin Polyclonal Antibody 50ul
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