85-6397-71　Crk II（Phospho Tyr221） Polyclonal Antibody 100ul　BT-AP08108

特徴

• 背景：This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from human CrkII around the phosphorylation site of Tyr221. AA range:187-236
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat, Monkey
• 適用：WB, IF, ICC, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Adapter molecule crk; CRK; Adapter molecule crk; Proto-oncogene c-Crk; p38
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