85-6386-32 Raf-1（Phospho Ser296） Polyclonal Antibody 100ul BT-AP07731
特徴
- 背景：This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K)| which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated| the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2| which in turn phosphorylate to activate the serine/threonine specific protein kinases| ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle| apoptosis| cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
仕様
- サイズ：100ul
- 抗原：The antiserum was produced against synthesized peptide derived from human C-RAF around the phosphorylation site of Ser296. AA range:271-320
- 免疫動物：Rabbit
- 交差性：Human, Mouse, Rat
- 適用：WB, IHC-p, IF, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：RAF proto-oncogene serine/threonine-protein kinase; RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6386-32
Raf-1（Phospho Ser296） Polyclonal Antibody 100ul
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85-6386-30
Raf-1（Phospho Ser296） Polyclonal Antibody 20ul
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85-6386-31
Raf-1（Phospho Ser296） Polyclonal Antibody 50ul
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