85-6385-28　RB3 Polyclonal Antibody 50ul　BT-AP07697

特徴

• 背景：RB3 (Stathmin-4), encoded by STMN4 gene, is a neuron-specific homologue of the SCG10/stathmin family proteins, possessing a unique N-terminal membrane-associated domain and the stathmin-like domain at the C terminus, which promotes microtubule (MT) catastrophe and/or tubulin sequestering. Stathmin is a ubiquitous cytosolic phosphoprotein, preferentially expressed in the nervous system, and described as a relay integrating diverse intracellular signaling pathways. RB3 is consistently up-regulated in differentiated neuroblastoma cells, and stable expression of transfected RB3 could induce differentiation, suggesting a role of RB3 during neuroblastoma differentiation. Moreover, increased RB3 is a unique response protein in the stathmin-related proteins following optical nerve axotomy and RB3 may be a critical target for neurodegenerative diseases.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human STMN4. AA range:140-189
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat
• 適用：WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：STMN4; Stathmin-4; Stathmin-like protein B3; RB3
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