85-6380-06　PDK1（Phospho Ser241） Polyclonal Antibody 20ul　BT-AP07524

特徴

• 背景：Catalytic activity:ATP + a protein = ADP + a phosphoprotein.|Phosphorylates and activates not only PKB/AKT| but also PKA| PKC-zeta| RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.|PTM:Phosphorylated on tyrosine and serine/threonine. Phosphorylation on Ser-241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser-241| leading to its own activation.|Belongs to the protein kinase superfamily.|Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDK1 subfamily.|Contains 1 PH domain.|Contains 1 protein kinase domain.|subcellular location:Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane.|subunit:Interacts with TUSC4.|tissue specificity:Appears to be expressed ubiquitously.|

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human PDK1 around the phosphorylation site of Ser241. AA range:210-259
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：3-phosphoinositide-dependent protein kinase 1; PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

• 【試薬に関するお問合せ】
• アズワン株式会社 試薬・プロセス材料グループ
• TEL：06-6447-8641
• FAX：06-6447-8642
• E-mail：[email protected]