85-6377-97　PSGL-1 Polyclonal Antibody 50ul　BT-AP07453

特徴

• 背景：SELPLG encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, selectin P ligand plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELPLG. AA range:1-50
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：SELPLG; P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162
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