85-6366-51　Perforin 1 Polyclonal Antibody 20ul　BT-AP07063

特徴

• 背景：The protein encoded by PRF1 (perforin 1) has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from the C-terminal region of human PRF1. AA range:451-500
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IHC, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)
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