85-6364-33　Met（Phospho Tyr1356） Polyclonal Antibody 20ul　BT-AP06990

特徴

• 背景：This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide| which has been shown to reduce lung fibrosis. Binding of its ligand| hepatocyte growth factor| induces dimerization and activation of the receptor| which plays a role in cellular survival| embryogenesis| and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma| hepatocellular carcinoma| and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human Met around the phosphorylation site of Tyr1356. AA range:1331-1380
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Hepatocyte growth factor receptor; MET; Hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met
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