85-6357-97　p300 Polyclonal Antibody 50ul　BT-AP06775

特徴

• 背景：EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human p300. AA range:1-50
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
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