85-6354-21　B2LA1 Polyclonal Antibody 20ul　BT-AP06632

特徴

• 背景：This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

仕様

• サイズ：20ul
• 抗原：Synthesized peptide derived from part region of human protein
• 免疫動物：Rabbit
• 交差性：Human, Mouse
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Bcl-2-related protein A1 ;Bcl-2-like protein 5;Bcl2-L-5;Hemopoietic-specific early response protein;Protein BFL-1;Protein GRS
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