85-6353-33　ATS4 Polyclonal Antibody 20ul　BT-AP06601

特徴

• 背景：This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradatio

仕様

• サイズ：20ul
• 抗原：Synthesized peptide derived from human protein . at AA range: 240-320
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：A disintegrin and metalloproteinase with thrombospondin motifs 4 ;ADAM-TS 4;ADAM-TS4;ADAMTS-4;EC 3.4.24.82;ADMP-1;Aggrecanase-1
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