85-6352-64　HDAC3（Phospho Ser424） Polyclonal Antibody 50ul　BT-AP06575

特徴

• 背景：Histones play a critical role in transcriptional regulation| cell cycle progression| and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human HDAC3 around the phosphorylation site of Ser424. AA range:379-428
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, IHC-p, IF, ICC, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Histone deacetylase 3; HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45
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