85-6342-42　FKBP1A/B Polyclonal Antibody 20ul　BT-AP06228

特徴

• 背景：The protein encoded by this gene is a member of the immunophilin protein family| which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels| and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse| deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants| encoding the same protein| have been identified. The human genome contains five pseudogenes related to this gene| at least one of which is transcribed.

仕様

• サイズ：20ul
• 抗原：Synthesized peptide derived from human FKBP1A/B
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：IHC-p, IF, WB
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：FKBP1A/B
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